The LEED credits DesignBuilder can calculate are:

Under Energy & Atmosphere (EA):
 
- Minimum Energy Performance prerequisite 2 (required)
- Optimize Energy Performance credit 1
 
Under Indoor Environmental Quality (EQ):
 
- Minimum Indoor Air Quality prerequisite 1 (required)
- Increased Ventilation EQ credit 2
- Daylight & Views: Daylight EQ credit 8.1